Step 1: Enzyme Inhibition – Once ingested, Tadalafil works by suppressing the PDE5 enzyme in the body. This enzyme is responsible for the breakdown of cyclic GMP, a substance that relaxes smooth muscle tissues.
Step 2: Enhanced Vasodilation – By inhibiting PDE5, the medication allows blood to flow more freely through the vascular system, specifically targeting the tissues of the penis. This increased blood flow is essential for improving the firmness and quality of an erection.
Step 3: Sustained Physiological Response – When combined with sexual stimulation, the increased blood flow leads to a stronger, more reliable erection. Because Tadalafil has a long half-life, these medical effects remain active in the system for up to 36 hours.